A simple symptom assessment can differentiate between OAB, stress incontinence, and mixed incontinence.

OAB is associated with urgency (a strong, sudden desire to void); frequency (more than 8 times per 24 hours); and a large amount of urinary leakage in patients who have episodes of incontinence.

Patients with OAB are often unable to reach the toilet in time after an urge to void and usually wake up to pass urine during the night.

Urge urinary incontinence is caused by uncontrollable contractions of the detrusor muscle; there may be very little warning time, and the volume of leakage is usually large.

Stress incontinence occurs when the pressure on the bladder is greater than the urethral pressure, resulting in a sudden loss of urine (usually a small volume). Physical movement or activity — such as coughing, sneezing, running or heavy lifting — puts pressure (stress) on your bladder. Stress incontinence is not related to psychological stress. Stress incontinence is typically due to weakened or damaged pelvic floor muscles.

Mixed incontinence occurs when the symptoms of OAB and stress incontinence are present in the same person. Individuals with mixed incontinence may experience leakage of urine due to a sudden uncontrollable urge to urinate and when coughing or sneezing.

Urine leakage associated with physical activity is not a symptom of OAB.

**UriVArx® is a dietary supplement and not intended to treat OAB, incontinence or any medical condition or symptom.